Determination of TNFAIP3, CDS1 and MTAP gene expression in a population of large white pigs
In modern molecular biology and genetics, the study of gene expression plays a key role in understanding the mechanisms of development and functioning of living organisms. In pig farming, where breeding and genetics are important tools for improving animal productivity and resilience, gene expression analysis can provide valuable material for breeding programs. The article devoted to determining the expression of TNFAIP3, CDS1 and MTAP genes in a population of large white pigs is an in-depth study in the field of molecular genetics and animal breeding. The above-mentioned genes were selected in connection with their supposed role in regulating the immune response, metabolism and development of the body. As a result of real-time PCR analysis, differences in the expression of CDS1 (CDP-diacylglycerine synthase) genes in lung and kidney tissues were shown compared with expression in heart tissues. In addition, it was found that the expression level of the MTAR (methylthioadenosine phosphorylase) gene differs in lung and spleen tissues compared to other studied organs. The results of the study may have significant implications for pig breeding programs, as they provide information on genetic factors affecting the productivity, sustainability and quality of pig meat. In addition, the article may be of interest to a wide range of specialists in the field of molecular genetics, animal breeding and veterinary medicine, as it demonstrates the application of modern methods of molecular biology to solve urgent problems in animal husbandry.
Authors
- P.I. OTRADNOV (ORCID: https://orcid.org/0000-0002-1153-5815)
- A. A. Reshetnikova (ORCID: https://orcid.org/0000-0002-4874-2615)
- Natalia Anatolievna Zinovieva (ORCID: https://orcid.org/0000-0003-4017-6863)
- A.F. KONTE (ORCID: https://orcid.org/0000-0003-4877-0883)
- Елена Требунских (ORCID: https://orcid.org/0000-0002-5208-3376)
- В. В. Волкова (ORCID: https://orcid.org/0000-0002-2080-0182)
- А. А. Белоус (ORCID: https://orcid.org/0000-0001-7533-4281)
Institutions
- Institute for Animal Husbandry (RS)
Publication Details
- Journal
- Agrarian science
- Published
- 2025-02-18
- DOI
- https://doi.org/10.32634/0869-8155-2025-391-02-95-100
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Russian Science Foundation