Determination of TNFAIP3, CDS1 and MTAP gene expression in a population of large white pigs

In modern molecular biology and genetics, the study of gene expression plays a key role in understanding the mechanisms of development and functioning of living organisms. In pig farming, where breeding and genetics are important tools for improving animal productivity and resilience, gene expression analysis can provide valuable material for breeding programs. The article devoted to determining the expression of TNFAIP3, CDS1 and MTAP genes in a population of large white pigs is an in-depth study in the field of molecular genetics and animal breeding. The above-mentioned genes were selected in connection with their supposed role in regulating the immune response, metabolism and development of the body. As a result of real-time PCR analysis, differences in the expression of CDS1 (CDP-diacylglycerine synthase) genes in lung and kidney tissues were shown compared with expression in heart tissues. In addition, it was found that the expression level of the MTAR (methylthioadenosine phosphorylase) gene differs in lung and spleen tissues compared to other studied organs. The results of the study may have significant implications for pig breeding programs, as they provide information on genetic factors affecting the productivity, sustainability and quality of pig meat. In addition, the article may be of interest to a wide range of specialists in the field of molecular genetics, animal breeding and veterinary medicine, as it demonstrates the application of modern methods of molecular biology to solve urgent problems in animal husbandry.

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Publication Details

Journal
Agrarian science
Published
2025-02-18
DOI
https://doi.org/10.32634/0869-8155-2025-391-02-95-100
Citations
1
Primary Topic
Adipose Tissue and Metabolism
Type
article
Field-Weighted Citation Impact
1.16

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article

Determination of TNFAIP3, CDS1 and MTAP gene expression in a population of large white pigs

P.I. OTRADNOV, A. A. Reshetnikova, Natalia Anatolievna Zinovieva, A.F. KONTE et al.
1 citations
Agrarian science
Adipose Tissue and Metabolism
1.16
article

Determination of TNFAIP3, CDS1 and MTAP gene expression in a population of large white pigs

P.I. OTRADNOV, A. A. Reshetnikova, Natalia Anatolievna Zinovieva, A.F. KONTE, Елена Требунских, В. В. Волкова, А. А. Белоус
article en
1 citations

Abstract

In modern molecular biology and genetics, the study of gene expression plays a key role in understanding the mechanisms of development and functioning of living organisms. In pig farming, where breeding and genetics are important tools for improving animal productivity and resilience, gene expression analysis can provide valuable material for breeding programs. The article devoted to determining the expression of TNFAIP3, CDS1 and MTAP genes in a population of large white pigs is an in-depth study in the field of molecular genetics and animal breeding. The above-mentioned genes were selected in connection with their supposed role in regulating the immune response, metabolism and development of the body. As a result of real-time PCR analysis, differences in the expression of CDS1 (CDP-diacylglycerine synthase) genes in lung and kidney tissues were shown compared with expression in heart tissues. In addition, it was found that the expression level of the MTAR (methylthioadenosine phosphorylase) gene differs in lung and spleen tissues compared to other studied organs. The results of the study may have significant implications for pig breeding programs, as they provide information on genetic factors affecting the productivity, sustainability and quality of pig meat. In addition, the article may be of interest to a wide range of specialists in the field of molecular genetics, animal breeding and veterinary medicine, as it demonstrates the application of modern methods of molecular biology to solve urgent problems in animal husbandry.

Agrarian science(2)
Institute for Animal Husbandry (RS)
Russian Science Foundation
Openalex Percentile: Top 25%
Adipose Tissue and Metabolism
1.16
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