Comprehensive Survey of AACR GENIE Database of Tumor Mutation Burden (TMB) Among All Three Classes (I, II, III) of BRAF Mutated (BRAF+) NSCLC
A substantial proportion of <i>BRAF</i>+ NSCLC patients exhibited a TMB ≥ 10, among all three classes of <i>BRAF</i> mutation classification, including <i>BRAF</i> V600E+ NSCLC. Class III mutations appeared to have the highest median TMB, followed by class II, and then class I.
Authors
- Kevin Shieh (ORCID: https://orcid.org/0000-0003-4339-2967)
- Misako Nagasaka (ORCID: https://orcid.org/0000-0001-5308-615X)
- Sai‐Hong Ignatius Ou (ORCID: https://orcid.org/0000-0002-1764-4975)
- Zhaohui Arter (ORCID: https://orcid.org/0000-0001-7394-7156)
Institutions
- University of California, Irvine (US)
- University of California, Irvine Medical Center (US)
- Community Cancer Center (US)
Publication Details
- Journal
- Lung Cancer Targets and Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/lctt.s493835
- Citations
- 3
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 2.42