Single‐cell transcriptomic atlas of different endometriosis indicating that an interaction between endometriosis‐associated mesothelial cells (EAMCs) and ectopic stromal cells may influence progesterone resistance
Single-cell RNA (ScRNA) atlas across types of endometriosis is established. Mesothelial cells are founded in ovarian endometriosis. Endometriosis-associated mesothelial cells (EAMCs) experience various level of epithelial-mesenchymal transition (EMT) process in different subtypes. EAMCs may exert an influence on progesterone resistance in stromal cells through intercellular communication mediated by the FN1-AKT pathway.
Authors
- Chongdong Liu (ORCID: https://orcid.org/0000-0003-3391-9964)
- Sheng‐Tao Hou (ORCID: https://orcid.org/0000-0001-9736-342X)
- Zhiqiang Zhang (ORCID: https://orcid.org/0000-0002-6848-4019)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-3082-8330)
- Shuhong Li (ORCID: https://orcid.org/0000-0001-5806-9148)
- Ying Jiang (ORCID: https://orcid.org/0000-0003-1235-4802)
- Hong Qu (ORCID: https://orcid.org/0000-0001-9570-7452)
Institutions
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/ctm2.70216
- Citations
- 5
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.49