Molecular Imaging of Ovarian Follicles and Tumors With Near‐Infrared II Bioconjugates (Adv. Mater. 7/2025)
Molecular Imaging Monitoring follicular development is crucial for evaluating female fertility and diagnosing infertility. This work introduces a novel NIR-II imaging strategy using FDA-approved ICG-conjugated hCG protein, enabling high-resolution, long-term tracking of early follicles. Beyond infertility diagnosis, this method also identifies ovarian tumors and micro-metastases, offering a groundbreaking tool for reproductive and oncological applications. More details can be found in article number 2414129 by Hao Chen, Yi Feng, and co-workers.
Authors
- Wenhao Gao (ORCID: https://orcid.org/0009-0007-7928-2678)
- Yi Feng (ORCID: https://orcid.org/0000-0002-7156-6023)
- Zi‐Han Chen (ORCID: https://orcid.org/0000-0002-3322-1489)
- Mingzhen Xu (ORCID: https://orcid.org/0000-0003-4011-8495)
- Kuinyu Lee (ORCID: https://orcid.org/0000-0002-2701-4037)
- Wenhan Lu (ORCID: https://orcid.org/0000-0003-3890-5553)
- Fan Zhang (ORCID: https://orcid.org/0000-0003-3311-8294)
- Xiaoyu Tong (ORCID: https://orcid.org/0000-0002-1343-6335)
- Hao Chen (ORCID: https://orcid.org/0000-0002-8470-5467)
- Zhiming Wang (ORCID: https://orcid.org/0000-0002-0201-8912)
- Yan Xiao (ORCID: https://orcid.org/0009-0009-2281-4375)
- Wei Hu (ORCID: https://orcid.org/0000-0001-8813-633X)
- Ruihu Song (ORCID: https://orcid.org/0000-0002-1606-9198)
- Zhao Fang (ORCID: https://orcid.org/0000-0003-3057-8738)
- Zhenle Pei (ORCID: https://orcid.org/0000-0002-8921-2872)
- Yu Wang (ORCID: https://orcid.org/0000-0003-1077-9305)
- Yicong Wang (ORCID: https://orcid.org/0000-0001-9102-4363)
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University (CN)
- Eye & ENT Hospital of Fudan University (CN)
- Shanghai Institute of Materia Medica (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- State Key Laboratory of Medical Neurobiology
Publication Details
- Journal
- Advanced Materials
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/adma.202570058
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00