Acute Systemic Sclerosis-Associated Cardiomyopathy That Improved With Glucocorticoids and Cyclophosphamide

Our patient presented with systolic dysfunction as opposed to diastolic dysfunction that is more typical in patients with SSc-cardiomyopathy. Endomyocardial biopsies lacked T-lymphocyte infiltration that may be due to sampling error because >17 samples are needed to diagnose myocarditis in >80% of cases.

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Publication Details

Journal
JACC Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1016/j.jaccas.2024.102948
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Acute Systemic Sclerosis-Associated Cardiomyopathy That Improved With Glucocorticoids and Cyclophosphamide

Sanjiv J. Shah, Jon W. Lomasney, Monique Hinchcliff, Katherine V. Trinh et al.
JACC Case Reports
Systemic Sclerosis and Related Diseases
article

Acute Systemic Sclerosis-Associated Cardiomyopathy That Improved With Glucocorticoids and Cyclophosphamide

Sanjiv J. Shah, Jon W. Lomasney, Monique Hinchcliff, Katherine V. Trinh, A. Gustafson
article en

Abstract

Our patient presented with systolic dysfunction as opposed to diastolic dysfunction that is more typical in patients with SSc-cardiomyopathy. Endomyocardial biopsies lacked T-lymphocyte infiltration that may be due to sampling error because >17 samples are needed to diagnose myocarditis in >80% of cases.

JACC Case ReportsVol. 30(4)
Northwestern University (US)
National Heart, Lung, and Blood Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Good health and well-being
Openalex Percentile: Top 96%
Systemic Sclerosis and Related Diseases
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