Antimicrobial activity of chitosan against biofilm formation of klebsiella pneumonia and staphylococcus aureus associated with burn infections

The effect of chitosan on the biofilm-forming capacity of clinically isolated bacteria was investigated in this study. Chitosan (Biopolymer from Chitin) was made through a series of tests. Patients at Baghdad Medical City Hospital provided 133 clinically burn swap samples. According to the Vitik 2 test, Staphylococcus aureus was detected in 19 of them and Klebsiella pneumonia in 70 of them. Five S. aureus and twenty-five Klebsiella pneumonia were able to generate biofilm when cultivated in microtiter plates. According to the results, chitosan was more successful at stopping the formation of biofilm at a dosage of 1.6 mg/ml. These results imply that this drug may be used to treat Multidrug resistance bacteria (MDR) in the future.