Klebsiella pneumoniae urinary tract infection: A multicentric study highlights significant regional variations in antimicrobial susceptibility across India
Oral treatment options for <i>K. pneumoniae</i> cystitis are rapidly decreasing. Northern and southern India showed significant differences in antimicrobial susceptibility, highlighting the importance of local antibiograms for promoting antimicrobial stewardship. For uncomplicated cystitis, co-trimoxazole (54%) may be the empirical choice. Good susceptibility to fosfomycin was observed (89%). The empirical use of fluoroquinolones, cephalosporins, and amoxicillin-clavulanic acid has been discouraged. Piperacillin-tazobactam and aminoglycosides are carbapenem-sparing agents.
Authors
- Jyotsna Agarwal (ORCID: https://orcid.org/0000-0003-0568-7959)
- Shaika Farooq (ORCID: https://orcid.org/0000-0003-2903-2607)
- Asfia Sultan (ORCID: https://orcid.org/0000-0003-0343-9513)
- Rajeev N. Soman (ORCID: https://orcid.org/0000-0003-1578-9932)
- Hiba Sami (ORCID: https://orcid.org/0000-0002-4594-852X)
- Reba Kanungo (ORCID: https://orcid.org/0000-0002-3859-3628)
- Neelam Taneja (ORCID: https://orcid.org/0000-0003-1198-6138)
- Shalini Malhotra (ORCID: https://orcid.org/0000-0001-5186-1618)
- Sarita Mohapatra (ORCID: https://orcid.org/0000-0002-8311-4112)
- Areena Hoda Siddiqui (ORCID: https://orcid.org/0000-0002-2524-1711)
- Abdullah Balkhair (ORCID: https://orcid.org/0000-0001-6911-5568)
- Aruna Poojary (ORCID: https://orcid.org/0000-0002-2757-3912)
- Bhaskar Thakuria (ORCID: https://orcid.org/0000-0001-6775-7639)
- Suneeta Meena (ORCID: https://orcid.org/0000-0003-2927-0840)
- Meher Rizvi (ORCID: https://orcid.org/0000-0002-8769-947X)
- Sudip Kumar Dutta (ORCID: https://orcid.org/0000-0002-9534-4150)
- Sarman Singh (ORCID: https://orcid.org/0000-0002-0749-9647)
- Isabella Princess (ORCID: https://orcid.org/0000-0003-2329-5692)
- Ashish Jitendranath (ORCID: https://orcid.org/0000-0003-2132-332X)
- Bradley J. Langford (ORCID: https://orcid.org/0000-0001-5467-6776)
- Zaaima Al Jabri
- Keith H. St. John (ORCID: https://orcid.org/0009-0009-0623-7424)
- Renu Gur (ORCID: https://orcid.org/0000-0002-5051-681X)
- Razan Al Zadjali
- Nainaraj Ilanchezhiyan
- Manodeep Sen
- Sanjeev Singh (ORCID: https://orcid.org/0000-0002-5375-1209)
- Fatima Khan (ORCID: https://orcid.org/0000-0002-7629-0935)
- Aarti Gupta (ORCID: https://orcid.org/0000-0002-4838-5574)
- Maria Khan (ORCID: https://orcid.org/0000-0002-1492-172X)
- Ken Masters (ORCID: https://orcid.org/0000-0003-3425-5020)
- Azza AL Mamari
- Amal Malehi
- Raman Sardana (ORCID: https://orcid.org/0009-0000-9700-7791)
- Balvinder Mohan
- Narendra Pal Singh
- Pawan Kapoor
- Amina Al Jardani
- Sheela Devi
- Mannu Jain
- Vellore Ramanathan Yamunadevi
- H. Tahir
- Arwa Al Rajaibi
- Nisha Goyal (ORCID: https://orcid.org/0000-0002-8828-1139)
- Rugma Rajendradas
Institutions
- Amrita Institute of Medical Sciences and Research Centre (IN)
- Indraprastha Apollo Hospitals (IN)
- Apollo Hospitals (IN)
- Central Pollution Control Board (IN)
- Government Medical College (IN)
- Jawaharlal Nehru Medical College Hospital (IN)
- Pondicherry Institute of Medical Sciences (IN)
- Aligarh Muslim University (IN)
- University College of Medical Sciences (IN)
- Patna Medical College and Hospital (IN)
- University of Toronto (CA)
- Integral University (IN)
- Ambedkar University Delhi (IN)
- Aarupadai Veedu Medical College & Hospital (IN)
- Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital (IN)
- Breach Candy Hospital (IN)
- Guru Teg Bahadur Hospital (IN)
- Sardar Vallabhbhai National Institute of Technology Surat (IN)
- Healthcare Infection Society (GB)
- Fortis Memorial Research Institute (IN)
- Jupiter Medical Center (US)
- Dr. Ram Manohar Lohia Institute of Medical Sciences (IN)
- Institute of Management Sciences Peshawar (PK)
- Sree Gokulam Medical College and Research Foundation (IN)
- Apollo Hospitals (IN)
- Ministry of Health (OM)
- Ministry of Agriculture and Fisheries (OM)
- Biological Consulting Services (United States) (US)
- International Foundation for Integrated Care (GB)
- Sultan Qaboos University Hospital (OM)
- Apollo Hospitals (IN)
- Al Nahdha Hospital (OM)
- Post Graduate Institute of Medical Education and Research (IN)
- Sultan Qaboos University (OM)
- Institute of Medical Sciences (IN)
- All India Institute of Medical Sciences (IN)
- Amrita Vishwa Vidyapeetham (IN)
Publication Details
- Journal
- IJID Regions
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1016/j.ijregi.2025.100605
- Citations
- 2
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.18
Funders
- Sultan Qaboos University