ILF3 inhibits p-AMPK expression to drive non-alcoholic fatty liver disease progression
ILF3 promotes the evolution of NAFLD by inhibiting the expression of p-AMPK. The knockdown of ILF3 activates the AMPK signaling pathway, alleviating the severity of NAFLD. These findings underscore the function of ILF3 in the pathogenesis of NAFLD and demonstrate its viability as a treatment focus and diagnostic indicator.
Authors
- Yanli Zou (ORCID: https://orcid.org/0000-0001-5793-8065)
- Ting Zhan (ORCID: https://orcid.org/0000-0003-0622-7890)
- M. Chen
- Min Huang (ORCID: https://orcid.org/0000-0002-4330-0340)
- Xiaodong Huang (ORCID: https://orcid.org/0009-0009-9274-7032)
- Wei Chen (ORCID: https://orcid.org/0000-0002-1919-594X)
- Jie Tan (ORCID: https://orcid.org/0000-0002-0909-2904)
- Jiaxi Liu (ORCID: https://orcid.org/0000-0003-2140-9000)
- Zheng Han (ORCID: https://orcid.org/0000-0002-6927-8567)
- Tian Xia (ORCID: https://orcid.org/0009-0007-5007-2431)
- Xiao-Rong Tian
- Xiulin Yang
Institutions
- Wuhan Third Hospital (CN)
Publication Details
- Journal
- World Journal of Hepatology
- Published
- 2025-02-20
- DOI
- https://doi.org/10.4254/wjh.v17.i2.101691
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00