Quantitative CT imaging characteristics of patients with chronic obstructive pulmonary disease with different eosinophil levels: a retrospective observational study using linked data from a tertiary hospital in China
Hypereosinophilic COPD (EOS ≥2% or EOS ≥150/µL or EOS ≥300/µL) appears to have less bronchial thickening and better lung function. Notably, in patients with EOS ≥300/µL, the EI of the right upper lobe is reduced. These findings provide valuable insights into the role of EOS in COPD pathophysiology.
Authors
- Shouliang Qi (ORCID: https://orcid.org/0000-0003-0977-1939)
- Xiaoxue Wu
- Kai Wang (ORCID: https://orcid.org/0000-0003-4802-520X)
- Shuiqing Zhao (ORCID: https://orcid.org/0000-0001-9991-773X)
- Lirong Du
- Ruiying Wang (ORCID: https://orcid.org/0000-0001-6224-8480)
- Xiansheng Liu (ORCID: https://orcid.org/0000-0002-9598-5054)
Institutions
- Shanxi Academy of Medical Sciences (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Northeastern University (CN)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1136/bmjopen-2024-088887
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China International Medical Foundation