Periodontitis-related myocardial fibrosis by expansion of collagen-producing SiglecF+ neutrophils
This study demonstrated that long-lasting PD-aggravated MI prognosis by expanding scar-associated SiglecF+ neutrophils into the heart and highlighted the clinical relevance of oral health examination for treating MI in a holistic fashion.
Authors
- Xuekui Wang (ORCID: https://orcid.org/0000-0002-9149-7002)
- Xingbo Yang (ORCID: https://orcid.org/0000-0002-5798-4448)
- Baowei Zhang (ORCID: https://orcid.org/0000-0001-7043-0370)
- Jiayi Liang
- Canqing Yu (ORCID: https://orcid.org/0000-0002-0019-0014)
- Chunrong Pan (ORCID: https://orcid.org/0009-0000-1925-9213)
- Yao Sun (ORCID: https://orcid.org/0000-0002-4323-0506)
- Congjiao Hu (ORCID: https://orcid.org/0000-0001-7163-0470)
- Ruhua Deng
- Yaozu Xiang
- Kai Jiang (ORCID: https://orcid.org/0000-0002-1917-0208)
- Yang Chen (ORCID: https://orcid.org/0000-0003-0308-6930)
- Dandan Wang (ORCID: https://orcid.org/0000-0001-6334-6330)
- Xun Yuan (ORCID: https://orcid.org/0009-0003-7285-3010)
- Yue Xu (ORCID: https://orcid.org/0000-0001-5953-4830)
Institutions
- Tongji University (CN)
- Peking University (CN)
- Office of Readiness and Response (US)
- Shanghai East Hospital (CN)
- Imperial College London (GB)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-01-26
- DOI
- https://doi.org/10.1093/eurheartj/ehaf049
- Citations
- 18
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 26.37
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Shanghai Hospital Development Center
- Kementerian Pendidikan Malaysia
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities