Biomarkers of Radioresistance in Head and Neck Cancer: A New Beginning
The development of biomarkers of radioresistance in head and neck cancer may help personalize treatment. This commentary puts in context the findings of a secondary analysis of NRG/RTOG 9512, a trial of fractionation in T2N0 glottic cancer, which observed that NFE2L2/KEAP1/CUL3 mutations are correlated with local recurrence and disease-free survival. See related article by Guan et al., p. 1615.
Authors
- Yuan James Rao (ORCID: https://orcid.org/0000-0002-9938-2197)
Institutions
- George Washington University (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-4223
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00