Novel association of ocular myasthenia gravis with Brown syndrome in an adult

Brown syndrome is an ocular misalignment disorder affecting the superior oblique tendon-trochlea complex. We report a case of a 45-year-old woman with protracted symptoms of presumed idiopathic Brown syndrome later diagnosed as ocular myasthenia gravis. Acquired Brown syndrome secondary to ocular myasthenia gravis has not previously been reported in the literature. Ocular myasthenia gravis should be considered a differential in any patient presenting with vertical strabismus presenting as Brown syndrome.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1093/jscr/rjaf059
Primary Topic
Ophthalmology and Eye Disorders
Type
article
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article

Novel association of ocular myasthenia gravis with Brown syndrome in an adult

Amy T. Wang, Todd Goodwin
2 links
Journal of Surgical Case Reports
Ophthalmology and Eye Disorders
article

Novel association of ocular myasthenia gravis with Brown syndrome in an adult

Amy T. Wang, Todd Goodwin
article en

Abstract

Brown syndrome is an ocular misalignment disorder affecting the superior oblique tendon-trochlea complex. We report a case of a 45-year-old woman with protracted symptoms of presumed idiopathic Brown syndrome later diagnosed as ocular myasthenia gravis. Acquired Brown syndrome secondary to ocular myasthenia gravis has not previously been reported in the literature. Ocular myasthenia gravis should be considered a differential in any patient presenting with vertical strabismus presenting as Brown syndrome.

Journal of Surgical Case ReportsVol. 2025(2)
Townsville Hospital (AU), James Cook University (AU)
Good health and well-being
Openalex Percentile: Top 96%
Ophthalmology and Eye Disorders
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