Individualized Net Benefit of Intensive Blood Pressure Lowering Among Community‐Dwelling Older Adults in <scp>SPRINT</scp>
Among community-dwelling older adults with hypertension in SPRINT, almost all participants had a net benefit that favored a systolic BP target of < 120 mm Hg, but the magnitude of net benefit varied according to estimated risks and simulated preferences.
Authors
- Rebecca Scherzer (ORCID: https://orcid.org/0000-0002-1579-5390)
- Jarett D. Berry (ORCID: https://orcid.org/0000-0002-5004-8155)
- Joachim H. Ix (ORCID: https://orcid.org/0000-0002-8084-9869)
- Charles Ginsberg (ORCID: https://orcid.org/0000-0001-9408-3684)
- Richard L. Kravitz (ORCID: https://orcid.org/0000-0001-5575-529X)
- Daniel J. Tancredi (ORCID: https://orcid.org/0000-0002-3884-7907)
- Michelle M. Estrella (ORCID: https://orcid.org/0000-0002-8902-9576)
- Simon B. Ascher (ORCID: https://orcid.org/0000-0003-3465-4208)
- James A. de Lemos (ORCID: https://orcid.org/0000-0003-2211-7261)
- Mitra Jamshidian (ORCID: https://orcid.org/0000-0002-1849-0082)
- Michael G. Shlipak (ORCID: https://orcid.org/0000-0002-9559-204X)
- Rebecca S. Boxer (ORCID: https://orcid.org/0000-0002-3715-616X)
Institutions
- San Francisco General Hospital (US)
- University of California, San Francisco (US)
- University of California San Diego (US)
- VA San Diego Healthcare System (US)
- San Francisco VA Health Care System (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- The University of Texas Health Science Center at Tyler (US)
Publication Details
- Journal
- Journal of the American Geriatrics Society
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1111/jgs.19395
- Citations
- 9
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 12.49
Funders
- U.S. Department of Veterans Affairs
- American Heart Association
- American Society of Nephrology
- AstraZeneca
- Baxter International
- National Institutes of Health
- Abbott Diagnostics
- Takeda Pharmaceuticals International
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute of Neurological Disorders and Stroke
- National Center for Advancing Translational Sciences