Effect of blood alcohol on the diagnostic accuracy of glial fibrillary acidic protein and ubiquitin carboxy‐terminal hydrolase L1 for traumatic intracranial hemorrhage: A <scp>TRACK‐TBI</scp> study
Modestly and significantly elevated BAL does not lower the diagnostic accuracy of GFAP and UCH-L1 for predicting traumatic intracranial injury on CT. These biomarkers may be useful in decreasing avoidable brain CT imaging in persons with acute alcohol intoxication.
Authors
- Lindsay D. Nelson (ORCID: https://orcid.org/0000-0001-5258-953X)
- Frederick K. Korley (ORCID: https://orcid.org/0000-0003-4920-8278)
- Mark Harris (ORCID: https://orcid.org/0000-0002-1598-225X)
- Raquel C. Gardner (ORCID: https://orcid.org/0000-0003-4028-440X)
- David O. Okonkwo (ORCID: https://orcid.org/0000-0002-7444-2851)
- Amy J. Markowitz (ORCID: https://orcid.org/0000-0001-9314-2814)
- Ramon Diaz‐Arrastia (ORCID: https://orcid.org/0000-0001-6051-3594)
- Sonia Jain (ORCID: https://orcid.org/0000-0001-8408-1247)
- Pratik Mukherjee (ORCID: https://orcid.org/0000-0001-7473-7409)
- Esther L. Yuh (ORCID: https://orcid.org/0000-0002-1180-2274)
- Ava M. Puccio (ORCID: https://orcid.org/0000-0003-2569-9607)
- Sabrina R. Taylor (ORCID: https://orcid.org/0000-0003-4867-1922)
- John K. Yue (ORCID: https://orcid.org/0000-0001-9694-7722)
- Kevin Wang (ORCID: https://orcid.org/0000-0002-9343-6473)
- Geoffrey T. Manley
- Xiaoying Sun
Institutions
- Penn Presbyterian Medical Center (US)
- University of California, San Francisco (US)
- University of California, Irvine (US)
- Medical College of Wisconsin (US)
- University of Michigan (US)
- Sheba Medical Center (IL)
- University of California San Diego (US)
- UPMC Presbyterian (US)
- Human Longevity (United States) (US)
- University of Pittsburgh Medical Center (US)
- Neurological Surgery (US)
- Morehouse School of Medicine (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Academic Emergency Medicine
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1111/acem.15109
- Citations
- 6
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 8.34
Funders
- U.S. Department of Defense
- National Institute of Neurological Disorders and Stroke