Identification and multi-dimensional validation of mitochondrial permeability transition-driven necrosis-related model to assess the prognosis and immunotherapy value in breast cancer
We developed a risk model with excellent predictive efficacy based on MPTdn and revealed that BCL2A1, SCUBE2, NPY1R and CLIC6 could be used as the biomarkers, laying a solid foundation for investigations of therapeutic targets of breast cancer.
Authors
- Liuliu Quan (ORCID: https://orcid.org/0000-0003-4599-6174)
- Min Dou (ORCID: https://orcid.org/0000-0003-0987-5578)
- Jian Yue (ORCID: https://orcid.org/0009-0009-9868-0959)
- Jinsong Liu (ORCID: https://orcid.org/0000-0002-3239-6658)
- Wei Tong (ORCID: https://orcid.org/0000-0002-8834-4953)
- Peng Yuan (ORCID: https://orcid.org/0000-0003-3751-8850)
Institutions
- Bengbu Medical College (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1186/s40001-025-02370-4
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04