Lower-extremity muscle strength is associated with prognosis in patients with advanced or recurrent lung cancer: a retrospective, observational study

Handgrip strength and lower-extremity muscle strength were stronger predictors of prognosis compared to the SMI. Furthermore, physical inactivity was significantly associated with lower-extremity muscle strength. From a clinical perspective, evaluating lower-extremity strength and physical activity is essential, and implementing exercise interventions, including strategies to enhance physical activity levels, should be considered.