Ferroptosis emerges as the predominant form of regulated cell death in goat sperm cryopreservation

Our findings establish ferroptosis as the dominant regulated cell death form during goat sperm cryopreservation, providing novel insights into freezing-induced sperm damage mechanisms. These findings have significant implications for optimizing cryopreservation protocols and enhancing sperm viability after freezing-thawing.

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Publication Details

Journal
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Published
2025-02-18
DOI
https://doi.org/10.1186/s40104-025-01158-0
Citations
8
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
13.58

Funders

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article

Ferroptosis emerges as the predominant form of regulated cell death in goat sperm cryopreservation

Jian Zhang, Erhan Hai, Jiaxin Zhang, Boyuan Li et al.
8 citations
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Sperm and Testicular Function
13.58
article

Ferroptosis emerges as the predominant form of regulated cell death in goat sperm cryopreservation

Jian Zhang, Erhan Hai, Jiaxin Zhang, Boyuan Li, Yukun Song
article en
8 citations

Abstract

Our findings establish ferroptosis as the dominant regulated cell death form during goat sperm cryopreservation, providing novel insights into freezing-induced sperm damage mechanisms. These findings have significant implications for optimizing cryopreservation protocols and enhancing sperm viability after freezing-thawing.

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnologyVol. 16(1)
Inner Mongolia Agricultural University (CN)
Natural Science Foundation of Inner Mongolia
Good health and well-being
Openalex Percentile: Top 1%
Sperm and Testicular Function
13.58
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