A model for predicting bacteremia species based on host immune response

The results demonstrated that PLS-DA effectively differentiates between specific pathogen groups, and external validation confirmed the predictive model's utility. Given that bacterial culture confirmation may take several days, our study underscores the potential of combining routine assays with a machine-learning model as a valuable clinical decision-support tool. This approach could enable prompt and accurate treatment on the same day that patients present to the clinic.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2025-02-18
DOI
https://doi.org/10.3389/fcimb.2025.1451293
Primary Topic
Yersinia bacterium, plague, ectoparasites research
Type
article
Field-Weighted Citation Impact
0.00
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article

A model for predicting bacteremia species based on host immune response

Laura Shevy, Cristian Bologa, Angela Wandinger‐Ness, Tione Buranda et al.
Frontiers in Cellular and Infection Microbiology
Yersinia bacterium, plague, ectoparasites research
article

A model for predicting bacteremia species based on host immune response

Laura Shevy, Cristian Bologa, Angela Wandinger‐Ness, Tione Buranda, Stephen Young, Virginie Bondu, Peter C. Simons
article en

Abstract

The results demonstrated that PLS-DA effectively differentiates between specific pathogen groups, and external validation confirmed the predictive model's utility. Given that bacterial culture confirmation may take several days, our study underscores the potential of combining routine assays with a machine-learning model as a valuable clinical decision-support tool. This approach could enable prompt and accurate treatment on the same day that patients present to the clinic.

Frontiers in Cellular and Infection MicrobiologyVol. 15
University of New Mexico (US)
Openalex Percentile: Top 96%
Yersinia bacterium, plague, ectoparasites research
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