A model for predicting bacteremia species based on host immune response
The results demonstrated that PLS-DA effectively differentiates between specific pathogen groups, and external validation confirmed the predictive model's utility. Given that bacterial culture confirmation may take several days, our study underscores the potential of combining routine assays with a machine-learning model as a valuable clinical decision-support tool. This approach could enable prompt and accurate treatment on the same day that patients present to the clinic.
Authors
- Laura Shevy
- Cristian Bologa (ORCID: https://orcid.org/0000-0003-2232-4244)
- Angela Wandinger‐Ness (ORCID: https://orcid.org/0000-0003-0613-3157)
- Tione Buranda
- Stephen Young (ORCID: https://orcid.org/0000-0002-0376-6138)
- Virginie Bondu
- Peter C. Simons
Institutions
- University of New Mexico (US)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-02-18
- DOI
- https://doi.org/10.3389/fcimb.2025.1451293
- Primary Topic
- Yersinia bacterium, plague, ectoparasites research
- Type
- article
- Field-Weighted Citation Impact
- 0.00