Identification of cancer-associated fibroblast signature genes for prognostic prediction in colorectal cancer
The CAFs risk model accurately predicted prognosis, immune cell infiltration, and stromal estimates. The prognostic CAFs (CD177 and CCDC78) may be potential therapeutic targets for CRC.
Authors
- Jianjiao Ni (ORCID: https://orcid.org/0000-0003-3113-2586)
- Changpeng Han
- Qian Shi (ORCID: https://orcid.org/0000-0003-2634-9553)
- Yiheng Yang (ORCID: https://orcid.org/0000-0003-3169-6162)
- Jin Wei (ORCID: https://orcid.org/0009-0004-3803-9725)
- Haojie Yang (ORCID: https://orcid.org/0000-0002-8633-2713)
- Zhenyi Wang (ORCID: https://orcid.org/0000-0001-5653-9636)
- Shuo Huang (ORCID: https://orcid.org/0000-0002-4499-1702)
- Yixin Yan (ORCID: https://orcid.org/0000-0003-4167-9745)
- Jingen Lu (ORCID: https://orcid.org/0000-0003-2640-3775)
- Yuchang Lu
- Biao Liang
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
- Yueyang Hospital (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-02-18
- DOI
- https://doi.org/10.3389/fgene.2025.1476092
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- National Natural Science Foundation of China