Exploring the role of epigenetic regulation in cancer prognosis with epigenetic score
The epigenetic scoring system developed in this investigation represents an innovative approach that demonstrates remarkable potential in forecasting survival trajectories across diverse cancer types. These groundbreaking insights not only illuminate the intricate interactions between epigenetic mechanisms and gene expression regulation in oncological contexts, but also indicate that the derived epigenetic metric could potentially emerge as a significant prognostic biomarker for cancer outcomes.
Authors
- Rongxiao Dai
- Ruiguang Zhang
- Qi Xu (ORCID: https://orcid.org/0000-0003-3963-4193)
- Sheng Jin (ORCID: https://orcid.org/0000-0001-6110-0783)
Institutions
- Dalian Medical University (CN)
- Jiading District Central Hospital (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
- Shanghai University of Medicine and Health Sciences (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-18
- DOI
- https://doi.org/10.3389/fphar.2025.1538205
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61