Newly identified species from the dog dental plaque microbiome highlight little overlap with humans
Understudied pet-associated microbiomes represent a rich source for the discovery of microbial taxa important for pet and human health. From a cohort of 23 dogs, we sampled and metagenomically sequenced 64 dental plaque microbiomes, generating 1945 metagenome-assembled genomes spanning 347 microbial species, including 277 undercharacterized species without cultivated representatives. Integration with human microbiome data revealed the dog plaque microbiome is more diverse than - and shows little overlap (5.9% species in common) with - the human plaque microbiome, even though some shared periodontal pathobionts arise as a potential concern.
Authors
- Gloria Fackelmann (ORCID: https://orcid.org/0000-0003-1684-5983)
- Milka Malešević (ORCID: https://orcid.org/0000-0001-9769-0471)
- Hrituraj Dey
- Nicola Segata (ORCID: https://orcid.org/0000-0002-1583-5794)
- Claudia Mengoni (ORCID: https://orcid.org/0000-0001-9629-2930)
- Vitor Heidrich (ORCID: https://orcid.org/0000-0001-6617-9187)
- Nemanja Stanisavljević (ORCID: https://orcid.org/0000-0001-5576-1833)
- Goran Vukotić (ORCID: https://orcid.org/0000-0001-9343-6214)
- Federica Armanini (ORCID: https://orcid.org/0009-0007-4030-2002)
Institutions
- University of Trento (IT)
- University of Belgrade (RS)
- European Institute of Oncology (IT)
Publication Details
- Journal
- npj Biofilms and Microbiomes
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1038/s41522-025-00665-2
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- European Commission
- Research Executive Agency