Nanostructured materials as potent platforms for cancer chemoimmunotherapy

Combinatorial chemoimmunotherapy has emerged as a potent approach in cancer treatment, offering the advantages of combining two treatment strategies (i.e., chemotherapy and immunotherapy), thereby reducing drug dosages and improving therapeutic outcomes. Nanomaterial-assisted drug delivery systems have garnered significant attention in chemoimmunotherapy for encapsulating and delivering therapeutic agents, as they can simultaneously target both cancer and immune cells, promoting drug accumulation with excellent therapeutic efficacy and minimal toxic side effects. This mini-review focuses on various aspects of immunotherapy and chemoimmunotherapy in cancer treatment and discusses several nanomaterial-assisted drug delivery systems used in chemoimmunotherapy.