Primary HIV-1 infection presenting with nephrotic-range proteinuria and severe acute kidney injury mimicking imported Lassa fever
Severe AKI requiring hemodialysis is a rare manifestation of PHI and may be associated with several conditions, most commonly PHI-associated rhabdomyolysis with tubulotoxic myoglobinuria. Severe AKI in PHI may also occur as a complication of MCD manifesting with nephrotic-range proteinuria. PHI should be considered in the differential diagnosis in patients presenting with severe proteinuria and AKI in the setting of febrile multiple organ dysfunction syndromes, including hemorrhagic fever diseases.
Authors
- Philipp Enghard (ORCID: https://orcid.org/0000-0002-7254-3931)
- Dirk Schürmann (ORCID: https://orcid.org/0000-0002-6879-9213)
- Leif Erik Sander (ORCID: https://orcid.org/0000-0002-0476-9947)
- Frieder Pfäfflin (ORCID: https://orcid.org/0000-0003-2777-2548)
- Miriam Songa Stegemann (ORCID: https://orcid.org/0000-0002-7968-0429)
- Stephan Achterberg (ORCID: https://orcid.org/0000-0002-0309-3244)
- Ralf Schindler (ORCID: https://orcid.org/0000-0001-5327-9138)
- Wolfgang Schneider
Institutions
- Humboldt-Universität zu Berlin (DE)
- Nierenzentrum Heidelberg (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Infection
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1007/s15010-024-02466-9
- Primary Topic
- Parvovirus B19 Infection Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Charité – Universitätsmedizin Berlin