Mosquito mutations F290V and F331W expressed in acetylcholinesterase of the sand fly Phlebotomus papatasi (Scopoli): biochemical properties and inhibitor sensitivity
These novel carbamates could be developed as efficacious insecticides, with improved specificity and safety for use in sand fly or mosquito populations expressing the mutant AChEs.
Authors
- Kevin B. Temeyer (ORCID: https://orcid.org/0000-0003-0180-218X)
- Fan Tong (ORCID: https://orcid.org/0000-0002-1692-2769)
- Paul R. Carlier (ORCID: https://orcid.org/0000-0002-6683-285X)
- Kristie G. Schlechte (ORCID: https://orcid.org/0000-0003-2263-8921)
- Jeffrey R. Bloomquist (ORCID: https://orcid.org/0000-0002-9136-4998)
- Qiao‐Hong Chen (ORCID: https://orcid.org/0000-0001-6753-1824)
- Adalberto Á. Pérez de León (ORCID: https://orcid.org/0000-0002-4115-7747)
Institutions
- Agricultural Research Service (US)
- University of Florida (US)
- University of Illinois Chicago (US)
- University of Chicago (US)
- San Joaquin Valley Agricultural Sciences Center (US)
- Université Bourgogne Franche-Comté (FR)
- Knipling-Bushland U.S. Livestock Insects Research Laboratory (US)
- Virginia Tech (US)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1186/s13071-025-06691-5
- Citations
- 1
- Primary Topic
- Cholinesterase and Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- U.S. Department of Defense
- U.S. Department of Agriculture
- Agricultural Research Service