Comprehensive Bioactive Compound Profiling of Artocarpus heterophyllus Leaves: LC-MS/MS Analysis, Antioxidant Potential, and Molecular Insights
Artocarpin and Sitosterol from <i>Artocarpus heterophyllus</i> leaf extracts demonstrate potent antioxidant, enzyme inhibitory, and tyrosinase inhibition activities. These findings underscore their potential for managing oxidative stress, inflammation, and pigmentation disorders, warranting further investigation into their bioavailability and formulation for therapeutic and cosmetic uses.
Authors
- Bambang Hernawan Nugroho (ORCID: https://orcid.org/0000-0002-2862-4857)
- Lelly Yuniarti (ORCID: https://orcid.org/0000-0002-6329-1277)
- Taufik Muhammad Fakih (ORCID: https://orcid.org/0000-0001-7155-4412)
- Maya Tejasari (ORCID: https://orcid.org/0000-0001-8398-7397)
- R. Anita Indriyanti (ORCID: https://orcid.org/0000-0001-5279-8032)
- Erni Maryam
Institutions
- Islamic University of Indonesia (ID)
- Universitas Jenderal Achmad Yani (ID)
- Bandung Islamic University (ID)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/dddt.s507658
- Citations
- 8
- Primary Topic
- Bioactive natural compounds
- Type
- article
- Field-Weighted Citation Impact
- 6.45
Funders
- Kementerian Pendidikan, Kebudayaan, Riset, dan Teknologi