Detecting the preoperative peripheral blood systemic immune-inflammation index (SII) as a tool for early diagnosis and prognosis of gallbladder cancer

Preoperative SII correlates strongly with CEA, CA125, and CA19-9 levels. The combined use of SII and tumor markers offers high diagnostic value for early GBC detection and robust predictive value for postoperative mortality. Preoperative SII serves as an IRF for poor prognosis in GBC patients.

Authors

Institutions

Publication Details

Journal
BMC Immunology
Published
2025-02-18
DOI
https://doi.org/10.1186/s12865-025-00683-x
Citations
8
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
8.36
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Detecting the preoperative peripheral blood systemic immune-inflammation index (SII) as a tool for early diagnosis and prognosis of gallbladder cancer

Jun Xu, Ping Yin, Zhiyong Shi, Feifei Qiao et al.
8 citations
BMC Immunology
Inflammatory Biomarkers in Disease Prognosis
8.36
article

Detecting the preoperative peripheral blood systemic immune-inflammation index (SII) as a tool for early diagnosis and prognosis of gallbladder cancer

Jun Xu, Ping Yin, Zhiyong Shi, Feifei Qiao, Baoping Jiao, Feng Liu
article en
8 citations

Abstract

Preoperative SII correlates strongly with CEA, CA125, and CA19-9 levels. The combined use of SII and tumor markers offers high diagnostic value for early GBC detection and robust predictive value for postoperative mortality. Preoperative SII serves as an IRF for poor prognosis in GBC patients.

BMC ImmunologyVol. 26(1)
Shanxi Medical University (CN), Shanxi Provincial Cancer Hospital (CN), First Hospital of Shanxi Medical University (CN), Second Hospital of Shanxi Medical University (CN), Cancer Hospital of Chinese Academy of Medical Sciences (CN)
Good health and well-being
Openalex Percentile: Top 2%
Inflammatory Biomarkers in Disease Prognosis
8.36
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Detecting the preoperative peripheral blood systemic immune-inflammation index (SII) as a tool for early diagnosis and prognosis of gallbladder cancer — Jun Xu, Ping Yin, et al. · BMC Immunology (2025) | TGRS Research Map | TGRS