Individual mHLA-DR trajectories in the ICU as predictors of early infections following liver transplantation: a prospective observational study
Our findings highlight mHLA-DR as an early predictor of post-LT infections. Monitoring post-LT immune function through mHLA-DR expression could guide individualized management strategies to improve outcomes. Trial registration The study was registered in the ClinicalTrials.gov registry: NCT03995537, date: June 20, 2019.
Authors
- Kayvan Mohkam (ORCID: https://orcid.org/0000-0002-9695-0902)
- Sasha Pantel
- Alice Blet (ORCID: https://orcid.org/0000-0003-3885-9569)
- Fanny Lebossé (ORCID: https://orcid.org/0000-0002-3411-1580)
- Térésa Antonini (ORCID: https://orcid.org/0009-0005-0441-4547)
- Morgane Gossez
- Arnaud Riff
- G. Monneret
- Céline Guichon (ORCID: https://orcid.org/0000-0003-2854-7668)
- Fabien Zoulim (ORCID: https://orcid.org/0000-0002-2245-0083)
- J. Dumortier
- Maxime Bodinier (ORCID: https://orcid.org/0000-0002-8691-385X)
- Laurent Heyer
- Xavier Muller (ORCID: https://orcid.org/0000-0002-8849-5495)
- D Erard
- Estelle Peronnet (ORCID: https://orcid.org/0000-0002-6764-8931)
- Fabienne Venet (ORCID: https://orcid.org/0000-0003-0462-4235)
- Marie‐Charlotte Delignette (ORCID: https://orcid.org/0000-0001-6214-0111)
- François Villeret (ORCID: https://orcid.org/0000-0002-9327-4590)
- Tanguy Soustre
- Frédéric Aubrun (ORCID: https://orcid.org/0000-0003-4383-039X)
- Jean‐Yves Mabrut
Institutions
- Université Claude Bernard Lyon 1 (FR)
- École Normale Supérieure de Lyon (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Hôpital de la Croix-Rousse (FR)
- Hospices Civils de Lyon (FR)
- Physiopathologie, diagnostic et traitements des maladies musculo-squelettiques (FR)
- bioMérieux (France) (FR)
Publication Details
- Journal
- Critical Care
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1186/s13054-025-05305-x
- Citations
- 2
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.01