A New Technique for Anticoagulation and Prevention of Bleeding During Impella 5.5 Left Ventricular Assist Device Implantation

The Abiomed Impella 5.5 (Danvers, MA) is a temporary left ventricular assist device (LVAD) used to support patients during acute cardiogenic shock. It is a catheter-based micro-axial blood pump that is surgically implanted to provide up to 5.5 liters per minute (LPM) of cardiac augmentation. The pump is most frequently inserted through a right subclavicular incision to the axillary artery. Anticoagulation is used during the implant procedure and then maintained at a lower concentration during the duration of support. Inadequate anticoagulation can result in pump thrombosis with subsequent thromboembolization. Excess anticoagulation can result in surgical site bleeding and potential hematoma formation. This case series details three patients with a low-dose anticoagulation strategy. There were no adverse embolic or hemorrhagic events in the peri- or postoperative period.

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Publication Details

Journal
ASAIO Journal
Published
2025-02-18
DOI
https://doi.org/10.1097/mat.0000000000002401
Citations
2
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
1.35
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article

A New Technique for Anticoagulation and Prevention of Bleeding During Impella 5.5 Left Ventricular Assist Device Implantation

Hannah Copeland, Asim Mohammed, John Morton
2 citations
ASAIO Journal
Mechanical Circulatory Support Devices
1.35
article

A New Technique for Anticoagulation and Prevention of Bleeding During Impella 5.5 Left Ventricular Assist Device Implantation

Hannah Copeland, Asim Mohammed, John Morton
article en
2 citations

Abstract

The Abiomed Impella 5.5 (Danvers, MA) is a temporary left ventricular assist device (LVAD) used to support patients during acute cardiogenic shock. It is a catheter-based micro-axial blood pump that is surgically implanted to provide up to 5.5 liters per minute (LPM) of cardiac augmentation. The pump is most frequently inserted through a right subclavicular incision to the axillary artery. Anticoagulation is used during the implant procedure and then maintained at a lower concentration during the duration of support. Inadequate anticoagulation can result in pump thrombosis with subsequent thromboembolization. Excess anticoagulation can result in surgical site bleeding and potential hematoma formation. This case series details three patients with a low-dose anticoagulation strategy. There were no adverse embolic or hemorrhagic events in the peri- or postoperative period.

ASAIO JournalVol. 71(12)
Community Health Systems - Lutheran Hospital (US), Community Health Network (US)
Good health and well-being
Openalex Percentile: Top 22%
Mechanical Circulatory Support Devices
1.35
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A New Technique for Anticoagulation and Prevention of Bleeding During Impella 5.5 Left Ventricular Assist Device Implantation — Hannah Copeland, Asim Mohammed, et al. · ASAIO Journal (2025) | TGRS Research Map | TGRS