Evidence of <i>Babesia microti</i> penetration of hepatocytes based on <i>in vitro</i> and <i>in vivo</i> studies
<i>B. microti</i> in intermediate hosts can infect erythrocytes, lymphocytes, and other cells, such as hepatocytes. <i>B. microti</i> affects liver cells directly in <i>in vitro</i> conditions and causes significant liver dysfunction in infected animals. The observed alterations in the blood vessels, including the adhesion of erythrocytes and thrombocytes to the vessel endothelium, provided compelling evidence that the infection of the intermediate host, <i>B. microti</i>, results in haemodynamic disturbances that significantly impact liver dysfunction.
Authors
- Jarosław Paluch (ORCID: https://orcid.org/0000-0001-7675-0623)
- Krzysztof Niemczuk (ORCID: https://orcid.org/0000-0003-1611-9770)
- Łukasz Chajec (ORCID: https://orcid.org/0000-0001-6455-9063)
- Danuta Urbańska-Jasik (ORCID: https://orcid.org/0000-0001-7673-7242)
- Marta Albertyńska (ORCID: https://orcid.org/0000-0003-4729-9823)
- Hubert Okła (ORCID: https://orcid.org/0000-0001-7210-2995)
- Krzysztof Jasik (ORCID: https://orcid.org/0000-0003-3974-6507)
- P Pol (ORCID: https://orcid.org/0000-0001-7025-8689)
- Monika Szymańska-Czerwińska (ORCID: https://orcid.org/0000-0001-8974-0870)
- Weronika Rupik (ORCID: https://orcid.org/0000-0002-9496-7524)
Institutions
- Jan Długosz University (PL)
- Medical University of Silesia (PL)
- National Research Institute of Animal Production (PL)
- Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences (PL)
- Departamento de Epidemiología (GT)
- University of Silesia in Katowice (PL)
Publication Details
- Journal
- Annals of Agricultural and Environmental Medicine
- Published
- 2025-02-18
- DOI
- https://doi.org/10.26444/aaem/200775
- Primary Topic
- Agricultural pest management studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00