Analytical performance evaluation and optimization of serum 25(OH)D LC-MS/MS measurement

Precision, trueness and MU improved after applying the optimized method. Nonetheless, more efforts are needed to ensure the reliability and accuracy of 25(OH)D measurements in clinical laboratories in China.

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Publication Details

Journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Published
2025-02-18
DOI
https://doi.org/10.1515/cclm-2024-1416
Citations
2
Primary Topic
Vitamin D Research Studies
Type
article
Field-Weighted Citation Impact
2.94

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article

Analytical performance evaluation and optimization of serum 25(OH)D LC-MS/MS measurement

Chuanbao Zhang, Huafen Liu, Wei Guo, Meiliang Gong et al.
2 citations
Clinical Chemistry and Laboratory Medicine (CCLM)
Vitamin D Research Studies
2.94
article

Analytical performance evaluation and optimization of serum 25(OH)D LC-MS/MS measurement

Chuanbao Zhang, Huafen Liu, Wei Guo, Meiliang Gong, Zheng Cao, Jun Xia, Xiaofen Yuan, Xianzhang Huang, Weiyan Zhou, Xuhui She, Yuanli Mao, Yuhang Deng, Wenxiang Chen, Qianwen Zhang, Ling Qiu, Yulong Cong
article en
2 citations

Abstract

Precision, trueness and MU improved after applying the optimized method. Nonetheless, more efforts are needed to ensure the reliability and accuracy of 25(OH)D measurements in clinical laboratories in China.

Clinical Chemistry and Laboratory Medicine (CCLM)Vol. 63(7)
Guangzhou University of Chinese Medicine (CN), Sun Yat-sen University (CN), Capital Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Fudan University (CN), Peking Union Medical College Hospital (CN), Chinese PLA General Hospital (CN), Kingmed Diagnostics (CN), Zhongshan Hospital of Xiamen University (CN), Zhongshan Hospital (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), Zhejiang Provincial People's Hospital (CN), National Center for Clinical Laboratories (CN), Huashan Hospital (CN), Beijing Obstetrics and Gynecology Hospital (CN), Hangzhou Medical College (CN), Guangzhou Medical University (CN)
National Science and Technology Major Project
Partnerships for the goals
Openalex Percentile: Top 12%
Vitamin D Research Studies
2.94
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