Comparative Diagnostic Accuracy of Ultrasound, MRI, and Fine-Needle Aspiration Biopsy in the Preoperative Evaluation of Parotid Gland Tumors

<b>Background:</b> The objective of this study was to compare the value of ultrasound (US), magnetic resonance imaging (MRI), and US-guided fine-needle aspiration biopsy (FNAB) in the preoperative evaluation of parotid tumors. <b>Methods:</b> A three-year prospective study, including 35 patients, was conducted. Preoperative ultrasound, MRI, and US-guided FNAB were performed on each patient, after which an imaging and cytological diagnosis was obtained. Each patient underwent surgical treatment. The imaging and cytological diagnoses were compared with the histopathological reports. <b>Results:</b> Ultrasound and MRI showed the same diagnostic performance in discriminating benign from malignant parotid tumors: sensitivity-80%, specificity-97%, and accuracy-94%. In this regard, FNAB registered a sensitivity, specificity, and accuracy of 100%, 97%, and 97%, respectively. US, MRI, and FNAB were recorded as having high diagnostic accuracy in the detection of pleomorphic adenoma and Warthin tumors. <b>Conclusions:</b> Ultrasound and US-guided FNAB allow for the preoperative differential diagnosis of parotid tumors located in the superficial lobe. When US and FNAB results are inconclusive, MRI becomes mandatory.