Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response
Circumferential noninvasive imaging of the AHO pathways was done in vivo. Segmental SC anatomy was seen, consistent with the known segmental nature of trabecular AHO. Segmental SC anatomical response to a muscarinic agonist was also observed. Segmental glaucoma drug response around the circumference of AHO pathways is an observation that may influence patient response to glaucoma treatments.
Authors
- Alex S. Huang (ORCID: https://orcid.org/0000-0001-9024-9608)
- Cheng Sun (ORCID: https://orcid.org/0000-0002-2744-0896)
- Junghun Kweon (ORCID: https://orcid.org/0000-0002-7538-7663)
- Daniel Kim (ORCID: https://orcid.org/0000-0001-8907-6420)
- Raymond Fang (ORCID: https://orcid.org/0000-0003-3887-0143)
- Hao F. Zhang
- Pengpeng Zhang
Institutions
- Northwestern University (US)
- University of California San Diego (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1167/iovs.66.2.47
- Citations
- 8
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 13.66
Funders
- Glaucoma Research Foundation
- Research to Prevent Blindness
- Santen
- Heidelberg Engineering
- National Institutes of Health
- Allergan
- University of California, San Diego