Empty large liposomes reduce cartilage degeneration in osteoarthritic rats by forming a lubricative coating
Reduction in cartilage degeneration by MM-II in OA rats is likely mediated through formation of a lubricative layer at the cartilage surface, though additional mechanisms could be mediating pain reduction demonstrated in clinical trials.
Authors
- Keren Turjeman (ORCID: https://orcid.org/0000-0002-2062-2662)
- Gilles Sarfati
- Rany Rotem
- Ronny Pinkus
- Haytam Kasem
- Roni Wechsler
- Yechezkel Barenholz
- Alison M. Bendele
Institutions
- Hebrew University of Jerusalem (IL)
- Azrieli College of Engineering Jerusalem (IL)
- Hadassah Medical Center (IL)
- Pivot (US)
- Fresenius Medical Care (Germany) (DE)
Publication Details
- Journal
- Osteoarthritis and Cartilage
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1016/j.joca.2025.02.774
- Citations
- 5
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 8.34