Mechanism of action of Danlou tablets affecting MAFLD via KEAP1-mediated oxeiptosis
Our findings suggest that DLT promotes Triglyceride catabolism and inhibit de novo fatty acid synthesis by affecting the activation of the oxeiptosis pathway, suggesting a potential therapeutic strategy for ameliorating NAFLD.
Authors
- Xiaofei Sun (ORCID: https://orcid.org/0000-0001-7026-4317)
- Yuan Cao (ORCID: https://orcid.org/0000-0002-5635-9253)
- Lianqun Jia (ORCID: https://orcid.org/0000-0003-0923-6987)
- Jingxuan Zhu
- Meiling Zhang (ORCID: https://orcid.org/0000-0002-8882-2564)
- Nan Song
- Jiaxin Wang (ORCID: https://orcid.org/0009-0003-1445-2358)
- Qun Wang (ORCID: https://orcid.org/0000-0003-1014-8677)
Institutions
- Liaoning University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1016/j.jep.2025.119521
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71