Association Between Polygenic Risk Scores and Treatment Response to Antidepressants, Benzodiazepines, and Antihistamines in Anxiety and Depression

Real-world data suggest that monotherapy with benzodiazepines or antihistamines can be predicted from PRSs related to anxiety, depression, and schizophrenia.

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Publication Details

Journal
Biological Psychiatry Global Open Science
Published
2025-02-18
DOI
https://doi.org/10.1016/j.bpsgos.2025.100470
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
0.00

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article

Association Between Polygenic Risk Scores and Treatment Response to Antidepressants, Benzodiazepines, and Antihistamines in Anxiety and Depression

Doug Speed, Hampus Grönvall, Fara Tabrizi, Fredrik Åhs et al.
2 links
Biological Psychiatry Global Open Science
Treatment of Major Depression
article

Association Between Polygenic Risk Scores and Treatment Response to Antidepressants, Benzodiazepines, and Antihistamines in Anxiety and Depression

Doug Speed, Hampus Grönvall, Fara Tabrizi, Fredrik Åhs, Amelie Markant
article en

Abstract

Real-world data suggest that monotherapy with benzodiazepines or antihistamines can be predicted from PRSs related to anxiety, depression, and schizophrenia.

Biological Psychiatry Global Open ScienceVol. 5(3)
University of Bremen (DE), Aarhus University (DK), Mid Sweden University (SE)
Karolinska Institutet, Vetenskapsrådet, Riksbankens Jubileumsfond
Good health and well-being
Openalex Percentile: Top 96%
Treatment of Major Depression
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