Rapid thawing enhances tissue destruction in a mouse model of cutaneous cryoablation: Insights into oxidative stress and neutrophil activation
Rapid thawing during cryoablation enhances neutrophil and lymphocyte infiltration, increases oxidative stress, and induces cell death, leading to greater tissue destruction in mice. Dermatologists should consider employing rapid thawing techniques during cryoablation when higher therapeutic intensities are required.
Authors
- Mai Ishikawa (ORCID: https://orcid.org/0000-0001-5873-8727)
- Takao Iwawaki (ORCID: https://orcid.org/0000-0001-8753-1979)
- Ryoko Torii (ORCID: https://orcid.org/0000-0002-1083-9550)
- Sachiko Ogino (ORCID: https://orcid.org/0000-0002-5026-7972)
- Sei‐ichiro Motegi (ORCID: https://orcid.org/0000-0001-8286-0669)
- Akiko Sekiguchi (ORCID: https://orcid.org/0000-0002-7016-337X)
- Akihiko Uchiyama (ORCID: https://orcid.org/0000-0002-1136-4649)
- Yoko Yokoyama (ORCID: https://orcid.org/0000-0002-9878-7555)
- Ryoko Akai
Institutions
- Kanazawa Medical University (JP)
- Gunma University (JP)
Publication Details
- Journal
- Journal of Dermatological Science
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1016/j.jdermsci.2025.02.003
- Citations
- 1
- Primary Topic
- Thermoregulation and physiological responses
- Type
- article
- Field-Weighted Citation Impact
- 1.16