Synchronous Bilateral Male Breast Cancer: A Case Report and Literature Review

Male breast cancer is an uncommon condition, representing less than 1% of all cancers in men and around 1% of all breast cancer cases. The majority of the data on male breast cancer comes from retrospective studies, as there are no randomized trials dedicated specifically to this population. Consequently, treatment guidelines are often adapted from research on female breast cancer. While male breast cancer shares many similarities with female breast cancer, there are unique aspects that require special attention. We present the case of a 67-year-old man, with no history of familial breast cancer, gynecomastia, solid organ tumors or hormonal medication who presented with bilateral breast mass. Bilateral mastectomy with left axillary lymph node dissection and right sentinel lymph node were performed. The final histopathological examination confirmed the initial biopsy diagnosis, with the tumors classified Left breast: T3N2M0 and T1N0M0 in right breast according to the TNM breast cancer staging system with an immunohistochemical Luminal B profile, HER 2negative. The goal of this study is to raise awareness of breast cancer in men, aiming to promote early diagnosis and ultimately improve prognosis.

Publication Details

Journal
Journal of Case Reports and Medical History
Published
2025-02-18
DOI
https://doi.org/10.54289/jcrmh2500108
Primary Topic
Male Breast Health Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Synchronous Bilateral Male Breast Cancer: A Case Report and Literature Review

Journal of Case Reports and Medical History
Male Breast Health Studies
article

Synchronous Bilateral Male Breast Cancer: A Case Report and Literature Review

article en

Abstract

Male breast cancer is an uncommon condition, representing less than 1% of all cancers in men and around 1% of all breast cancer cases. The majority of the data on male breast cancer comes from retrospective studies, as there are no randomized trials dedicated specifically to this population. Consequently, treatment guidelines are often adapted from research on female breast cancer. While male breast cancer shares many similarities with female breast cancer, there are unique aspects that require special attention. We present the case of a 67-year-old man, with no history of familial breast cancer, gynecomastia, solid organ tumors or hormonal medication who presented with bilateral breast mass. Bilateral mastectomy with left axillary lymph node dissection and right sentinel lymph node were performed. The final histopathological examination confirmed the initial biopsy diagnosis, with the tumors classified Left breast: T3N2M0 and T1N0M0 in right breast according to the TNM breast cancer staging system with an immunohistochemical Luminal B profile, HER 2negative. The goal of this study is to raise awareness of breast cancer in men, aiming to promote early diagnosis and ultimately improve prognosis.

Journal of Case Reports and Medical History
Openalex Percentile: Top 96%
Male Breast Health Studies
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