Unveiling the Potential of Terahertz Technology for Non-Invasive Biomonitoring of Liver Tissue

Wireless biomonitoring is revolutionizing healthcare by empowering remote real-time patient monitoring, facilitating disease early detection, and improving disease management. This technology has the potential to transform the way various organs are monitored, including the silent sentinel, the liver, which is responsible for processing nutrients, filtering toxins and waste, producing proteins, and regulating blood sugar levels. Incor-porating terahertz technology with wireless biomonitoring will not only enable non-invasive intrabody communication but also empower sensing and detecting variations in tissue properties, enhancing disease early detection. Nevertheless, to utilize this technology, a clear understanding of the photothermal impact of terahertz radiation on the liver tissue is crucial for designing safe and efficient biomonitoring implanted devices/sensors. In this work, a COMSOL ® multiphysics model is developed to study the photothermal dynamics resulting from the terahertz electromagnetic radiation absorbed by the liver tissue. The effect of power, pulse duration, and shape, as well as the fat content in a fatty liver patient, are investigated. Results indicate that utilizing terahertz-based implant devices can have minimal to no thermal impact on the liver when designed with careful control of transmission power and duration tailored to individual patients to ensure liver health and safety.