Investigation of severe dengue outbreak in Maumere, East Nusa Tenggara, Indonesia: Clinical, serological, and virological features

The severe dengue outbreak in Maumere is caused by DENV-3 introduced from nearby islands. The high proportion of secondary infections likely contributes to the severity of the disease. The high percentage of anti-dengue neutralizing antibodies for multiple serotypes and the high proportion of anti-dengue IgG in young children suggests a history of dengue transmission with a high infection rate in the area.

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Publication Details

Journal
PLoS ONE
Published
2025-02-18
DOI
https://doi.org/10.1371/journal.pone.0317854
Citations
4
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
7.51
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article

Investigation of severe dengue outbreak in Maumere, East Nusa Tenggara, Indonesia: Clinical, serological, and virological features

Martin L. Hibberd, Marsha S. Santoso, Dionisius Denis, R. Tedjo Sasmono et al.
4 citations
PLoS ONE
Mosquito-borne diseases and control
7.51
article

Investigation of severe dengue outbreak in Maumere, East Nusa Tenggara, Indonesia: Clinical, serological, and virological features

Martin L. Hibberd, Marsha S. Santoso, Dionisius Denis, R. Tedjo Sasmono, Angela M. B. Boro, Rahma Hayati, Asep Purnama, Mario Bernardinus Realino Nara, Bunga Rana, D. Nugroho, Erlinda P. Gae, Benediktus Yohan Arman
article en
4 citations

Abstract

The severe dengue outbreak in Maumere is caused by DENV-3 introduced from nearby islands. The high proportion of secondary infections likely contributes to the severity of the disease. The high percentage of anti-dengue neutralizing antibodies for multiple serotypes and the high proportion of anti-dengue IgG in young children suggests a history of dengue transmission with a high infection rate in the area.

PLoS ONEVol. 20(2)
Eijkman Institute for Molecular Biology (ID), London School of Hygiene & Tropical Medicine (GB)
Good health and well-being
Openalex Percentile: Top 3%
Mosquito-borne diseases and control
7.51
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Investigation of severe dengue outbreak in Maumere, East Nusa Tenggara, Indonesia: Clinical, serological, and virological features — Martin L. Hibberd, Marsha S. Santoso, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS