Comparative Effectiveness and Safety of the <scp>JAK</scp> Inhibitors and Biologic Disease‐Modifying Antirheumatic Drugs in Treating Children With Nonsystemic Juvenile Idiopathic Arthritis: A Bayesian Meta‐Analysis of Randomized Controlled Trials
Overall, no significant evidence was found for efficacy and safety profiles in pairwise comparisons of JAKis and bDMARDs. Future studies will expand the meta-analysis by including non-RCT studies and individual participant data.
Authors
- Hermine I. Brunner (ORCID: https://orcid.org/0000-0001-9478-2987)
- Xiaomeng Yue (ORCID: https://orcid.org/0000-0002-4418-7079)
- Bin Huang (ORCID: https://orcid.org/0000-0001-9724-675X)
- Daniel J. Lovell (ORCID: https://orcid.org/0000-0003-1604-0130)
- Sandra Andorf (ORCID: https://orcid.org/0000-0002-3093-2568)
- Yu‐Xiang Li
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- ACR Open Rheumatology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/acr2.11788
- Citations
- 1
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Agency for Healthcare Research and Quality
- National Institute of Arthritis and Musculoskeletal and Skin Diseases