Three locally invasive infantile fibrosarcoma cases treated with larotrectinib
These cases emphasize the importance of advanced molecular studies, like next-generation sequencing, for childhood tumors and integrating research with clinical trials. tropomyosin receptor kinase inhibitor larotrectinib may offer a safe and effective alternative to chemotherapy for NTRK fusion-positive, metastatic, or unresectable tumors.
Authors
- Serap Karaman (ORCID: https://orcid.org/0000-0002-7428-3897)
- Şifa Şahin
- Gülşah Tanyıldız (ORCID: https://orcid.org/0000-0002-0455-2078)
- Yasin Yılmaz (ORCID: https://orcid.org/0000-0002-4811-5750)
- Zeynep Karakaş (ORCID: https://orcid.org/0000-0002-8835-3235)
- Ayşegül Ünüvar (ORCID: https://orcid.org/0000-0002-4730-7697)
- Deniz Tuğcu (ORCID: https://orcid.org/0000-0002-4374-7134)
- Doğa Dalay (ORCID: https://orcid.org/0000-0002-6593-1805)
Institutions
- Istanbul University (TR)
Publication Details
- Journal
- The Turkish Journal of Pediatrics
- Published
- 2025-02-18
- DOI
- https://doi.org/10.24953/turkjpediatr.2025.4557
- Citations
- 2
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.04