Isolated Third Cranial Nerve Palsy Following Coronary Angiography: A Rare Neuro-Ophthalmologic Complication

Neurological complications following cardiac coronary angiography (CAG), such as ischemic stroke and neuro-ophthalmologic syndromes, are uncommon but significant. This report presents a rare case of isolated third cranial nerve palsy that developed after CAG, highlighting the potential risks associated with the procedure. A 51-year-old male with a history of hypertension and ischemic heart disease underwent CAG for non-ST-segment elevation myocardial infarction. Although the procedure and subsequent cardiac imaging results were normal, the patient developed sudden onset binocular diplopia, ptosis, and restricted eye movements in his left eye following CAG, indicative of left third cranial nerve palsy. Initial computed tomography (CT) and computed tomography angiography (CTA) scans were unremarkable, but a magnetic resonance imaging (MRI) revealed multiple recent lacunar infarcts, including one along the path of the left oculomotor nerve, suggesting an embolic cause. Neuro-ophthalmologic complications post-CAG, though rare, require early detection and intervention, emphasizing the need for preventive measures in at-risk patients.

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Journal
Cureus
Published
2025-02-18
DOI
https://doi.org/10.7759/cureus.79244
Primary Topic
Meningioma and schwannoma management
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article
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article

Isolated Third Cranial Nerve Palsy Following Coronary Angiography: A Rare Neuro-Ophthalmologic Complication

Ali H Alsaedi, Mahmoud M. Ismail, Nasser G Al Saedi, Omar S Basamh
1 links
Cureus
Meningioma and schwannoma management
article

Isolated Third Cranial Nerve Palsy Following Coronary Angiography: A Rare Neuro-Ophthalmologic Complication

Ali H Alsaedi, Mahmoud M. Ismail, Nasser G Al Saedi, Omar S Basamh
article en

Abstract

Neurological complications following cardiac coronary angiography (CAG), such as ischemic stroke and neuro-ophthalmologic syndromes, are uncommon but significant. This report presents a rare case of isolated third cranial nerve palsy that developed after CAG, highlighting the potential risks associated with the procedure. A 51-year-old male with a history of hypertension and ischemic heart disease underwent CAG for non-ST-segment elevation myocardial infarction. Although the procedure and subsequent cardiac imaging results were normal, the patient developed sudden onset binocular diplopia, ptosis, and restricted eye movements in his left eye following CAG, indicative of left third cranial nerve palsy. Initial computed tomography (CT) and computed tomography angiography (CTA) scans were unremarkable, but a magnetic resonance imaging (MRI) revealed multiple recent lacunar infarcts, including one along the path of the left oculomotor nerve, suggesting an embolic cause. Neuro-ophthalmologic complications post-CAG, though rare, require early detection and intervention, emphasizing the need for preventive measures in at-risk patients.

CureusVol. 17(2)
King Abdullah Medical City (SA)
Good health and well-being
Openalex Percentile: Top 95%
Meningioma and schwannoma management
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Isolated Third Cranial Nerve Palsy Following Coronary Angiography: A Rare Neuro-Ophthalmologic Complication — Ali H Alsaedi, Mahmoud M. Ismail, et al. · Cureus (2025) | TGRS Research Map | TGRS