The protective effects of a single dose myricetin application on CLP-induced rat sepsis model by analyzing some immune mechanisms
As a conclusion, the beneficial effect of myricetin on lung injury also involved inhibition of TLR4/NF-κB pathway, suppression of proinflammatory cytokines and induction of anti-inflammatory cytokine production, regulation of oxidant and anti-oxidant system parameters, and activating the NRF2/Keap1/HO-1 pathway.
Authors
- İsmail Can (ORCID: https://orcid.org/0000-0003-0569-5326)
- Murat KARAMESE
- Selina AKSAK KARAMESE
- Gülşen Babacan Yıldız (ORCID: https://orcid.org/0000-0003-0922-0969)
- Onur Başer (ORCID: https://orcid.org/0000-0001-7447-5672)
- Ali Guraslan
- Ihsan TOPLAOGLU
Institutions
- Kafkas University (TR)
- Department of Embryology (US)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1080/08923973.2025.2469227
- Citations
- 4
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 5.42