Temporal risk patterns of severe hypovolemia associated with sodium‐glucose cotransporter‐2 inhibitors in patients with type 2 diabetes mellitus: A self‐controlled case series study

SGLT2i use in patients with type 2 diabetes mellitus was associated with a higher risk of severe hypovolemia, particularly within the first 30 days of treatment initiation, with the highest risk observed during 22 to 28 days.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2025-02-18
DOI
https://doi.org/10.1111/dom.16259
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Temporal risk patterns of severe hypovolemia associated with sodium‐glucose cotransporter‐2 inhibitors in patients with type 2 diabetes mellitus: A self‐controlled case series study

Koji Kawakami, Atsushi Takayama, Kasumi Yokogawa, Mitsuhiro Shikamura
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
article

Temporal risk patterns of severe hypovolemia associated with sodium‐glucose cotransporter‐2 inhibitors in patients with type 2 diabetes mellitus: A self‐controlled case series study

Koji Kawakami, Atsushi Takayama, Kasumi Yokogawa, Mitsuhiro Shikamura
article en

Abstract

SGLT2i use in patients with type 2 diabetes mellitus was associated with a higher risk of severe hypovolemia, particularly within the first 30 days of treatment initiation, with the highest risk observed during 22 to 28 days.

Diabetes Obesity and MetabolismVol. 27(5)
Kyoto University (JP), Takeda (Japan) (JP)
Good health and well-being
Openalex Percentile: Top 96%
Diabetes Treatment and Management
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