Chromosomal and gonadal sex have differing effects on social motivation in mice
Gonadal and chromosomal sex have independent mechanisms of driving greater social motivation in females. Additionally, genes on the sex chromosomes may interact with neurodevelopmental risk genes to influence sex variation in atypical social behavior.
Authors
- Din Selmanovic (ORCID: https://orcid.org/0000-0002-5425-1476)
- Susan E. Maloney (ORCID: https://orcid.org/0000-0001-5585-4722)
- Simona Sarafinovska (ORCID: https://orcid.org/0000-0002-1456-7556)
- Katherine B. McCullough (ORCID: https://orcid.org/0000-0001-9752-5740)
- Sneha Chaturvedi (ORCID: https://orcid.org/0000-0003-2452-3685)
- Raylynn G. Swift (ORCID: https://orcid.org/0000-0003-2014-3642)
- Joseph D. Dougherty (ORCID: https://orcid.org/0000-0002-6385-3997)
Institutions
- Washington University in St. Louis (US)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1186/s13293-025-00690-y
- Citations
- 2
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Simons Foundation Autism Research Initiative
- National Institutes of Health