Co-Occurrence of Cytogenetic Abnormalities and High-Risk Disease in Newly Diagnosed and Relapsed/Refractory Multiple Myeloma
The association of ≥two HRCAs with the poorest outcome in NDMM and RRMM, and across treatment modalities, as demonstrated here for the first time to our knowledge, allows for more focused development of novel approaches to these patients with high unmet need.
Authors
- Pieter Sonneveld (ORCID: https://orcid.org/0000-0002-0808-2237)
- Franck Dubin (ORCID: https://orcid.org/0009-0006-5098-7319)
- Andréa Capra (ORCID: https://orcid.org/0000-0003-4799-7920)
- Jorge Acosta‐Reyes (ORCID: https://orcid.org/0000-0003-4303-3243)
- Mario Boccadoro (ORCID: https://orcid.org/0000-0001-8130-5209)
- Juan José Lahuerta (ORCID: https://orcid.org/0000-0002-3393-9570)
- Jesús F. San Miguel (ORCID: https://orcid.org/0000-0002-9183-4857)
- Alessandra Larocca (ORCID: https://orcid.org/0000-0002-2070-3702)
- María‐Victoria Mateos (ORCID: https://orcid.org/0000-0003-2390-1218)
- Francesca Gay (ORCID: https://orcid.org/0000-0002-8619-412X)
- Gordon C Cook (ORCID: https://orcid.org/0000-0003-1717-0412)
- Marc‐Andrea Baertsch (ORCID: https://orcid.org/0000-0002-4000-6904)
- Joan Bladé
- David Allan Cairns (ORCID: https://orcid.org/0000-0002-2338-0179)
- Anita K. Gandhi (ORCID: https://orcid.org/0000-0001-5512-1625)
- Pellegrino Musto (ORCID: https://orcid.org/0000-0003-3277-6594)
- Norma Carmen Gutierrez (ORCID: https://orcid.org/0000-0001-5834-9510)
- Rick Zhang
- Niels Weinhold (ORCID: https://orcid.org/0000-0002-5464-3234)
- Uta Bertsch (ORCID: https://orcid.org/0000-0001-5584-3951)
- Kwee Yong (ORCID: https://orcid.org/0000-0002-6487-276X)
- Marc S. Raab (ORCID: https://orcid.org/0000-0003-4181-6922)
- Sarah Brown (ORCID: https://orcid.org/0000-0002-7975-7537)
- Martin Kaiser (ORCID: https://orcid.org/0000-0002-3677-4804)
- K. Elias (ORCID: https://orcid.org/0000-0002-6226-1252)
- Sandrine Macé (ORCID: https://orcid.org/0000-0001-9263-6994)
- Graham Jackson (ORCID: https://orcid.org/0000-0003-0756-969X)
- Rakesh Popat (ORCID: https://orcid.org/0000-0001-6553-4618)
- Cong Li (ORCID: https://orcid.org/0000-0001-7731-8031)
Institutions
- University of Leeds (GB)
- Institute of Cancer Research (GB)
- Universidad de Salamanca (ES)
- Heidelberg University (DE)
- St James's University Hospital (GB)
- Erasmus MC (NL)
- University Hospital Heidelberg (DE)
- Sanofi (France) (FR)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Bristol-Myers Squibb (United States) (US)
- Hospital Universitario 12 De Octubre (ES)
- Deerfield (United States) (US)
- Sanofi (United States) (US)
- Royal Marsden Hospital (GB)
- Instituto de Investigación Biomédica de Salamanca (ES)
- Clinica Universidad de Navarra (ES)
- Cancer Research UK Clinical Trials Unit (GB)
- Centro de Investigación del Cáncer (ES)
- Takeda (United States) (US)
- Centro de Investigación Biomédica en Red de Cáncer (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- University College London (GB)
- Bristol-Myers Squibb (Switzerland) (CH)
- University of Turin (IT)
- University of Bari Aldo Moro (IT)
- Newcastle University (GB)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1200/jco-24-01253
- Citations
- 12
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 21.24