Factors, pregnancy outcomes, and management associated with non-reportable results in prenatal cell-free DNA testing
Repeated testing was not suitable for all cases with non-reportable results. Invasive prenatal diagnosis should be recommended for cases with MCA, cases with caution indications and with low fetal fraction for the first non-reportable results, cases with consecutive non-reportable cfDNA results. More attention should be paid to the cases with non-reportable cfDNA results, especially to the cases with non-reportable redraw testing results.
Authors
- Mingzhu Miao (ORCID: https://orcid.org/0000-0002-1342-8001)
- Huaixia Yin
- Xin Wu (ORCID: https://orcid.org/0000-0002-5005-6358)
- Xiang Ma (ORCID: https://orcid.org/0000-0003-2285-9206)
- Wang Ya (ORCID: https://orcid.org/0000-0002-0297-8227)
- Xi Wang (ORCID: https://orcid.org/0000-0002-5974-6363)
- Jiangtao Shi (ORCID: https://orcid.org/0000-0002-7296-7275)
- Jue Wang (ORCID: https://orcid.org/0009-0006-2492-3311)
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1007/s00404-025-07977-w
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- National Key Research and Development Program of China