Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma
Our integrated bioinformatic analysis elucidated that EGR1 directly regulates the production of IL33 in T2-asthma and provide insights underlying the progression of asthma.
Authors
- Zhengxiu Luo (ORCID: https://orcid.org/0000-0003-3029-9624)
- Jenil Patel (ORCID: https://orcid.org/0000-0002-4875-7390)
- Jinhua Fan
- Lin Chen (ORCID: https://orcid.org/0009-0005-8299-8322)
- Yan Zhao (ORCID: https://orcid.org/0000-0002-9198-4521)
- Yuanyuan Li (ORCID: https://orcid.org/0000-0001-9458-6169)
- Xinyang Wang (ORCID: https://orcid.org/0009-0005-9136-5551)
Institutions
- China International Science and Technology Cooperation (CN)
- Chongqing Maternal and Child Health Hospital (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1186/s12967-025-06116-y
- Citations
- 5
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 3.99
Funders
- Chongqing Medical University