Examining Different Methods to Assess Busulfan Exposure in Pediatric Hematopoietic Stem Cell Transplant Recipients

When switching between NCA and MBMs to estimate busulfan AUC cum in pediatric HSCT recipients, a change in the target AUC cum is likely required to maintain a similar drug exposure during therapeutic drug monitoring.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2025-02-18
DOI
https://doi.org/10.1097/ftd.0000000000001304
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Examining Different Methods to Assess Busulfan Exposure in Pediatric Hematopoietic Stem Cell Transplant Recipients

Rachael Lawson, Christopher Fraser, Stefanie Hennig, Christine E. Staatz
Therapeutic Drug Monitoring
Hematopoietic Stem Cell Transplantation
article

Examining Different Methods to Assess Busulfan Exposure in Pediatric Hematopoietic Stem Cell Transplant Recipients

Rachael Lawson, Christopher Fraser, Stefanie Hennig, Christine E. Staatz
article en

Abstract

When switching between NCA and MBMs to estimate busulfan AUC cum in pediatric HSCT recipients, a change in the target AUC cum is likely required to maintain a similar drug exposure during therapeutic drug monitoring.

Therapeutic Drug MonitoringVol. 47(3)
Queensland University of Technology (AU), The University of Queensland (AU), Children's Health Queensland Hospital and Health Service (AU)
Good health and well-being
Openalex Percentile: Top 96%
Hematopoietic Stem Cell Transplantation
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Examining Different Methods to Assess Busulfan Exposure in Pediatric Hematopoietic Stem Cell Transplant Recipients — Rachael Lawson, Christopher Fraser, et al. · Therapeutic Drug Monitoring (2025) | TGRS Research Map | TGRS