Toxic effects of prolonged propofol exposure on cardiac development in zebrafish larvae

In conclusion, our study indicates that propofol alters the structure and function of the developing zebrafish heart, with the mitochondrial-related gene agxt2 possibly being a target of its pharmacological effects.

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Publication Details

Journal
BMC Anesthesiology
Published
2025-02-18
DOI
https://doi.org/10.1186/s12871-025-02942-1
Citations
2
Primary Topic
Anesthesia and Neurotoxicity Research
Type
article
Field-Weighted Citation Impact
2.64

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article

Toxic effects of prolonged propofol exposure on cardiac development in zebrafish larvae

Xiaopan Luo, Hanwei Wei, Shaojie Qian, Jintao Liu et al.
2 citations
BMC Anesthesiology
Anesthesia and Neurotoxicity Research
2.64
article

Toxic effects of prolonged propofol exposure on cardiac development in zebrafish larvae

Xiaopan Luo, Hanwei Wei, Shaojie Qian, Jintao Liu, Xiaojun Li, Huizi Liu
article en
2 citations

Abstract

In conclusion, our study indicates that propofol alters the structure and function of the developing zebrafish heart, with the mitochondrial-related gene agxt2 possibly being a target of its pharmacological effects.

BMC AnesthesiologyVol. 25(1)
Zhejiang Provincial People's Hospital (CN), Hangzhou Medical College (CN)
Department of Education of Zhejiang Province
Good health and well-being
Openalex Percentile: Top 12%
Anesthesia and Neurotoxicity Research
2.64
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